When it comes to infectious disease, few evoke revulsion like parasites and particularly parasitic worms known as “helminths.” We’ve all heard winced after reading about the life cycle of the American hookworm, or Necator americanus. In their infective stage, their … Continue reading The Worm Doctors
The UK Biobank project is an open source large scale epidemiological project aimed at prospectively collecting data on large number of phenotypes and genotypes across large number of individuals (1). Specifically, the project aims to collect data on lifestyle, environmental … Continue reading All you need to know about UK biobank
While the more affluent societies of the West continue to debate the specter of genetically engineered babies, dozens of researchers around the world are using epigenetics to zero in on novel ways to fight the malaria parasite, which afflicts more … Continue reading Interrupting Epigenetics Factors to Thwart Malaria
What is DNA testing? Most of us know the term ‘DNA testing’, also known as genetic sequencing, from its use in crime solving and in paternity disputes (1). However, since the dawn of this century, considerable progress has been made … Continue reading A new era of direct-to-consumer genetic DNA testing: the hypes and realities
What is Multiple Myeloma? Multiple myeloma is a treatable but incurable cancer of the blood in which certain immune cells (known as plasma cells) accumulate in the bone marrow, which is the spongy tissue inside some bones where body’s blood … Continue reading What is the role of genetics in the development of Multiple Myeloma?
What is Gilbert’s Syndrome? Gilbert’s syndrome, also known as familial nonhemolytic jaundice or hyperbilirubinemia 1, is a common, benign genetic hepatic dysfunction that occurs when the liver does not process bilirubin correctly (the liver is not able to degrade bilirubin). … Continue reading The genetic basis of Gilbert’s Syndrome: an overview.
What is celiac disease? Celiac disease is an autoimmune disease (a failure of the body’s immune system that induces the body to attack its own tissues) in which gluten activates an immune response that destroys the villi, tiny finger-like protrusions … Continue reading Everything you need to know about the genetics of celiac disease
In the past few decades, DNA testing through DNA samples has grown tremendously with technological and medical advancements. DNA is commonly found on items that are physically touched such as clothing, drink bottles, hats, headphones, postage stamps, and tissues. To … Continue reading The Ins and Outs of DNA Samples
We all know that information is passed down from one generation to the next through genes. But what about another type of non-gene change in your DNA, called epigenetics? Literally meaning “above the genes”, epigenetic changes are chemical modifications to … Continue reading Changes in Your Genome Felt Throughout Generations
We use so many words to describe our backgrounds. We talk about heritage, ancestry, race, and ethnicity. Most of us use these words interchangeably, but they don’t mean the same thing. Cultural identify and genetic ancestry do not always line … Continue reading The Genetics of Culture (Hint: It doesn’t exist)